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ウイルス感染時の表皮角化細胞でのinterleukin-6産生調節機構：ムンプス感染表皮角化細胞を用いた研究
https://kindai.repo.nii.ac.jp/records/2002461
https://kindai.repo.nii.ac.jp/records/20024615f8ef14c-8d60-4709-924f-6f2fad174634
| 名前 / ファイル | ライセンス | アクション |
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AN00063584-19920325-0143.pdf (764.5 KB)
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| アイテムタイプ | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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| 公開日 | 2025-02-19 | |||||||||
| タイトル | ||||||||||
| タイトル | ウイルス感染時の表皮角化細胞でのinterleukin-6産生調節機構：ムンプス感染表皮角化細胞を用いた研究 | |||||||||
| 言語 | ja | |||||||||
| タイトル | ||||||||||
| タイトル | Analysis for the regulatory mechanism of interleukin-6 production in epidermal keratinocytes attacked by the viruses : study for using epidermal keratinocytes attacked by mumps virus | |||||||||
| 言語 | en | |||||||||
| 著者 |
織田, 知明
× 織田, 知明
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題 | interleukin-6, mumps virus, measles virus, rubella virus, human keratinocyte, molecular regulation | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学医学会 | |||||||||
| 言語 | ja | |||||||||
| bibliographic_information |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 17, 号 1, p. 143-152, 発行日 1992-03-25 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 03858367 | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | Interleukin-6 in epidermal keratinocytes has not been fully elucidated. Human trichilemmoma cell line, K-TL-1 cell line, was used to analyze the presence of both messenger ribonucleic acid (mRNA) transcripts of interleukin-6 (IL-6) and IL-6 protein. Whether IL-6 was synthesized and secreted by the attack of mumps virus (MV), measles virus (MeV) and rubella virus (RV) was determined. Of the three viruses, only MV enhanced IL-6 mRNA expression and production of IL-6 protein in K-TL-1 cell line. The addition of the MV particle alone into the culture media of K-TL-1 cells expressed IL-6 mRNA. The expression of IL-6 mRNA was enhanced at 15 minutes, 30 minutes, 1 and 2 hours in K-TL-1 cell line, but the expression of IL-6 mRNA returned to the steady-state levels at 6, 24, 48 and 72 hours. The expression of IL-6 mRNA in K-TL-1 cell line was completely inhibited by the addition of 5 μl/ml of polyclonal antibody to MV. These findings show that the binding of MV with K-TL-1 cell certainly causes the expression of IL-6 mRNA. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||
| 言語 | ja | |||||||||
