| アイテムタイプ |
紀要論文 / departmental bulletin paper(1) |
| 公開日 |
2025-04-10 |
| タイトル |
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|
タイトル |
PQQとCoQ10の正常ヒト表皮角化細胞における紫外線障害と創傷治癒に対する効果 |
|
言語 |
ja |
| タイトル |
|
|
タイトル |
Effects of PQQ and CoQ10 on UV damage and wound healing in normal human epidermal keratinocytes |
|
言語 |
en |
| 作成者 |
山田, 康枝
村井, 雅輝
鍬﨑, 夕菜
三村, 桂子
神谷, 尚希
|
| 言語 |
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|
言語 |
jpn |
| キーワード |
|
|
主題 |
normal human epidermal keratinocytes, pyrroloquinoline quinone, coenzymeQ10, UVB, scratch assay |
| 内容記述 |
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|
内容記述タイプ |
Abstract |
|
内容記述 |
UV damages DNA, phospholipids and proteins on cell, disturbs the structure and function of the living cells, and is thought to promote skin aging such as spots and wrinkles on the skin. In order to find a highly safe substance that has a protective effect against skin damage caused by UV and to investigate its mechanism of action, we investigated food-derived substances that might have a protective effect against damages of UVB damage using normal human epidermal keratinocytes (NHEK). A scratch assay was performed to investigate the wound healing effect of the same substance on NHEK. Pyrroloquinoline quinone (PQQ), and coenzymeQ10 (CoQ10) were known to food-derived antioxidative product and to have different structure and origin. PQQ and CoQ10 showed a protective effect against damage caused by UVB, In the scratch assay, PQQ and CoQ10 showed significant wound healing effects. These results will be possible to use elucidated the mechanism of the protective effect. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
近畿大学工学部 |
|
言語 |
ja |
| 資源タイプ |
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|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 出版タイプ |
|
|
出版タイプ |
AM |
|
出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| ID登録 |
|
|
ID登録 |
10.15100/0002002383 |
|
ID登録タイプ |
JaLC |
| 収録物識別子 |
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|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
2434592X |
| 書誌情報 |
ja : 近畿大学工学部研究報告
en : Research reports of the Faculty of Engineering, Kindai University
号 58,
p. 85-89,
発行日 2025-02-20
|
AN00063799-20250220-0085.pdf (7.9 MB)
