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胃癌における神経浸潤の組織化学的検討
https://kindai.repo.nii.ac.jp/records/2002266
https://kindai.repo.nii.ac.jp/records/2002266bcf4513a-01fd-4f67-8d31-33d9f8f4f264
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00063584-19930325-0119.pdf (1.7 MB)
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| Item type | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||
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| 公開日 | 2025-01-17 | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | 胃癌における神経浸潤の組織化学的検討 | |||||||||||||
| 言語 | ja | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Histochemical studies on perineural invasion of gastric cancer | |||||||||||||
| 言語 | en | |||||||||||||
| 著者 |
渡辺, 勉
× 渡辺, 勉
× 田中, 晃
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| 言語 | ||||||||||||||
| 言語 | jpn | |||||||||||||
| キーワード | ||||||||||||||
| 主題 | gastric cancer, perineural invasion, laminin staining, peritoneal dissemination, type of recurrence, prognosis factor | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | departmental bulletin paper | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 出版者 名前 | ||||||||||||||
| 出版者 | 近畿大学医学会 | |||||||||||||
| 言語 | ja | |||||||||||||
| bibliographic_information |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 18, 号 1, p. 119-135, 発行日 1993-03-25 |
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| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 03858367 | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Perineural invasion (PNI) was studied histochemically in 283 cases of gastric cancer resected from 1982 to 1989 with pm or deeper invasion. PNI was studied in relation to the histopathological findings, the type of metastasis, the type of recurrence and outcome. Immunohistochemical staining of laminin was most useful for judgment of PNI as it stained the perineurium and nerve fasciculs in comparison with the other staining methods of HE, S-100 and silver-impregnation. PNI-positive cases were most frequently invasive type in gross appearance with the primary lesion occupying entire stomach, circular type in horizontal location, and stage III・IV and ssγ・se in depth of invasion. Of the peritoneal dissemination cases 72.4% were PNI-positive. Among the 216 curative resection cases, recurrence occurred in 103 cases, and was highly frequent in the cases with ssγ or deeper invasion. These recurrent cases were closely associated with ly, n and PNI. Peritoneal recurrence was found in 63.1% (65 cases) of the 103 recurrent cases. Peritoneal recurrence was most closely associated with PNI in the cases with pm and ss invasion. The 5-year survival rate of 71.3% for PNI-negative cases was significantly higher than the 23.7% for PNI-positive cases. Furthermore, the survival rate in PNI-positive cases was evidently low in the cases with pm and ss invasion. The results of multivariate analysis with a Cox regression model in the relationship between histopathological findings and outcome, revealed that the presence of PNI had the largest influence on the outcome, and was indicated to be useful as a prognostic factor in advanced gastric cancer. | |||||||||||||
| 言語 | en | |||||||||||||
| 内容記述 | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||||||
| 言語 | ja | |||||||||||||
