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成犬動脈壁におけるメタリックステントによる内膜肥厚に関する形態学的検討
https://kindai.repo.nii.ac.jp/records/2002078
https://kindai.repo.nii.ac.jp/records/2002078cd6b6a45-1f90-488c-9178-18925912d147
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00063584-19930925-0353.pdf (2.8 MB)
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| Item type | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||
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| 公開日 | 2024-12-05 | |||||||||
| タイトル | ||||||||||
| タイトル | 成犬動脈壁におけるメタリックステントによる内膜肥厚に関する形態学的検討 | |||||||||
| 言語 | ja | |||||||||
| タイトル | ||||||||||
| タイトル | Electronmicroscopical and immunohistochemical study on intimal thickening of canine aorta by metallic stent | |||||||||
| 言語 | en | |||||||||
| 著者 |
進藤, 啓
× 進藤, 啓
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題 | metallic stent, canine aorta, neointima, desmin, α_1-actin | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学医学会 | |||||||||
| 言語 | ja | |||||||||
| bibliographic_information |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 18, 号 3, p. 353-364, 発行日 1993-09-25 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 03858367 | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | As a basic experiment on the use of metallic stents to treat vascular stenosis, particularly restenosis after percutaneous transluminal angioplasty, a self-expandable metallic stent was inserted via the carotid artery through a catheter into a canine aorta and morphological changes of the aortic wall were examined electronmicroscopically and immunohistochemically. Four weeks after stenting, the metallic stent was completely covered by neointima and no thrombus was found. The surface of the intima was lined by immature endothelial cells with considerable microvilli. Both edema and cellular proliferation were responsible for thickening of the neointima. Two types of cells were recognized in the edematous neointima on electronmicroscopic observation, i. e., spindle-shaped fibroblastic cells and irregular smooth muscle-like cells. All of these cells were positive for α_1-actin, whereas spindle-shaped cells were positive for both α_1-actin and desmin, indicating mesenchymal characteristics. These results indicate that phenotype changes of proliferated smooth muscle cells may occur in neointima, i.e., from the synthetic type to the mature contractile type. The possible mechanisms of such intimal changes are discussed. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||
| 言語 | ja | |||||||||
