{"created":"2024-11-08T07:05:52.579540+00:00","id":2001994,"links":{},"metadata":{"_buckets":{"deposit":"b9c1c377-3b28-46a1-97df-303d8efaf1e2"},"_deposit":{"created_by":42,"id":"2001994","owners":[42],"pid":{"revision_id":0,"type":"depid","value":"2001994"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:02001994","sets":["14:2667:1728522335637:1728528474285"]},"author_link":[],"item_1693378644159":{"attribute_name":"研究分担者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"12601","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"東京大学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"長岡, 孝治","creatorNameLang":"ja"},{"creatorName":"nagaoka, Koji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"80649799","nameIdentifierScheme":"e-Rad"}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"12601","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"東京大学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"小林, 由香利","creatorNameLang":"ja"},{"creatorName":"Kobayashi, Yukari","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"40866919","nameIdentifierScheme":"e-Rad"}]}]},"item_1693381679919":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"=資源タイプ識別子":"http://purl.org/coar/resource_type/c_93fc","resourcetype":"report","resourceuri":"http://purl.org/coar/resource_type/c_93fc"}]},"item_30001_bibliographic_information17":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicNumberOfPages":"7","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2023)","bibliographic_titleLang":"ja"}]}]},"item_30001_creator2":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"34419","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kindai University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"垣見, 和宏","creatorNameLang":"ja"},{"creatorName":"Kakimi, Kazuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"80273358","nameIdentifierScheme":"e-Rad_Researcher"}]}]},"item_30001_description8":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"「見るだけでがんを攻撃するキラーT細胞を判別する顕微鏡・セルソーターを開発すること」をテーマに機能や分化が異なるT細胞の識別法を検討した。動的ゴーストイメージング (GMI: Ghost Motion Imaging) 法は、計測された細胞画像情報を、画像に再構成せずにデータのままで活用し、機械学習によりその細胞特性を捉えて高速判別する手法である。GMI技術を用いて、抗原刺激を受けて様々な機能を獲得し変化するT細胞の分化を、従来の細胞表面マーカーに対する蛍光抗体による識別ではなく、イメージ情報によってのみ識別する手法を確立した。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"We utilized GMI (Ghost Motion Imaging) technology to develop a novel cell analyzing and sorting system capable of identifying killer T cells that attack cancer simply by observing them.　The GMI method utilizes measured cell image data directly without reconstructing images, enabling rapid identification of cell characteristics through machine learning. Using GMI technology, we established a method to differentiate T cells with different functions and differentiation states, which acquire various functions upon antigen stimulation, solely based on image information rather than conventional identification via fluorescent antibodies targeting cell surface markers.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"研究分野：腫瘍免疫","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_30001_file22":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"22K19285seika.pdf","filesize":[{"value":"418.6 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://kindai.repo.nii.ac.jp/record/2001994/files/22K19285seika.pdf"},"version_id":"a72cdfb9-a409-479e-a584-b2c1e3682408"}]},"item_30001_funding_reference15":{"attribute_name":"助成情報","attribute_value_mlt":[{"subitem_award_numbers":{"subitem_award_number":"22K19285","subitem_award_uri":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22K19285/"},"subitem_award_titles":[{"subitem_award_title":"見るだけでがんを攻撃するキラーT細胞を判別する顕微鏡・セルソーターの開発","subitem_award_title_language":"ja"},{"subitem_award_title":"Development of a microscope/cell sorter to identify killer T cells that attack cancer simply by observing them","subitem_award_title_language":"en"}],"subitem_funder_names":[{"subitem_funder_name":"独立行政法人日本学術振興会","subitem_funder_name_language":"ja"},{"subitem_funder_name":"Japan Society for the Promotion of Science","subitem_funder_name_language":"en"}]}]},"item_30001_language10":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_30001_subject7":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"GMI","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"CTL","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"キラーT細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"AI","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"機械学習","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"T細胞活性化","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_30001_title0":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"見るだけでがんを攻撃するキラーT細胞を判別する顕微鏡・セルソーターの開発","subitem_title_language":"ja"},{"subitem_title":"Development of a microscope/cell sorter to identify killer T cells that attack cancer simply by observing them","subitem_title_language":"en"}]},"item_30001_version_type12":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_title":"見るだけでがんを攻撃するキラーT細胞を判別する顕微鏡・セルソーターの開発","item_type_id":"40001","owner":"42","path":["1728528474285"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-11-08"},"publish_date":"2024-11-08","publish_status":"0","recid":"2001994","relation_version_is_last":true,"title":["見るだけでがんを攻撃するキラーT細胞を判別する顕微鏡・セルソーターの開発"],"weko_creator_id":"42","weko_shared_id":-1},"updated":"2024-12-09T05:52:13.625490+00:00"}