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セボフルレンおよびハロセンのモルモット洞房結節活動電位に及ぼす影響
https://kindai.repo.nii.ac.jp/records/2001785
https://kindai.repo.nii.ac.jp/records/2001785c45eb5cd-493f-463d-a2a0-0481b345fb19
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
AN00063584-19940625-0287.pdf
|
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| Item type | ☆紀要論文 / Departmental Bulletin Paper(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2024-09-04 | |||||||||
| タイトル | ||||||||||
| タイトル | セボフルレンおよびハロセンのモルモット洞房結節活動電位に及ぼす影響 | |||||||||
| 言語 | ja | |||||||||
| タイトル | ||||||||||
| タイトル | Effects of sevoflurane and halothane on action potentials of the sinoatrial node in guinea pigs | |||||||||
| 言語 | en | |||||||||
| 著者 |
平松, 謙二
× 平松, 謙二
|
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題 | sinoatrial node, action potential, sevoflurane, halothane, atropine | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 版 | ||||||||||
| 出版タイプ | AM | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||
| 出版者 名前 | ||||||||||
| 出版者 | 近畿大学医学会 | |||||||||
| 言語 | ja | |||||||||
| 書誌情報 |
ja : 近畿大学医学雑誌 en : Medical Journal of Kinki University 巻 19, 号 2, p. 287-296, 発行日 1994-06-25 |
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| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| 収録物識別子 | 03858367 | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Abstract | |||||||||
| 内容記述 | The effects of sevoflurane and halothane on the electrophysiologic properties of the isolated spontaneously beating sinoatrial (SA) node in the guinea pig were examined. The piece of right atria containing the SA node was perfused with Krebs' solution and gassed with 5% CO_2 in O_2. During administration of the test solutions that were equilibrated with 1%, 2%, 3% or 4% sevoflurane or with 1% or 2% halothane, respectively, the following changes were observed. Introduction of the these anesthetics (sevoflurane and halothane) for fifteen minutes produced a significant decrease in the sinus rate, decreases in the slope of phase 0 and phase 4, and a increase in the action potential duration. At higher concentrations, 3% or 4% for seroflurane and 2% for halothane, these anesthetics significantly decreased the action potential amplitude and its overshoot. There was no change in the threshold potential or maximum diastolic potential. It is concluded that the decrease in the slope of phase 4 and the increase in the action potential duration by both sevoflurane and halothane lowered the sinus rate of the sinoatrial node in the guinea pig. | |||||||||
| 言語 | en | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | 本文データはCiNiiから複製したものである。 | |||||||||
| 言語 | ja | |||||||||
