{"created":"2024-04-23T07:57:06.636905+00:00","id":2001124,"links":{},"metadata":{"_buckets":{"deposit":"f97ac40d-945e-4fa2-ae23-3f83824430e8"},"_deposit":{"created_by":42,"id":"2001124","owners":[42],"pid":{"revision_id":0,"type":"depid","value":"2001124"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:02001124","sets":["14:923:1477:1713338090072"]},"author_link":[],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-06-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"97","bibliographicPageStart":"91","bibliographicVolumeNumber":"23","bibliographic_titles":[{"bibliographic_title":"近畿大学医学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Medical Journal of Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"心室性期外収縮は，基礎疾患を有する症例に出現することが多いが，明らかな基礎疾患のない症例にも認められる．近年，抗不整脈剤の催不整脈作用が問題となっており，心室性期外収縮に対する薬剤の選択が重要となってきている．そこで，24時間ホルター心電図を用いてtriggered activityを主たる機序とすると考えられる症例に対するβ1受容体拮抗薬であるbisoprololの有効性を検討した．対象は24時間ホルター心電図を施行し，単形性の心室性期外収縮が3000個/日以上認められ，明らかな基礎疾患を有しない31例に対してLorenz-Plot法，日内変動を用いて，本薬剤の有効性の解析を行った．全症例において有効率は51.6%であった．Lorenz-Plot法における分類においてはFixed type : 37.5%，Dependent type : 80.0%，Mixed type : 52.8%，Scattered type : 40.0%の有効率を示し，bisoprololはDependent typeを示す症例に最も有効であった．また，日内変動における分類においては，全日型 : 46.2%，昼間型 : 64.3%，夜間型 : 25.0%の有効率を示し，昼間型を示す症例に最も有効であった．以上よりtriggered activityを主たる機序とすると考えられるLorenz-Plot法によるDependent typeを示す症例にbisoprololが最も有効であることが示唆された．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"本文データはCiNiiから複製したものである。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学医学会","subitem_publisher_language":"ja"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03858367","subitem_source_identifier_type":"PISSN"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kinki University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"伊澤, 弘","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kinki University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"塚本, 哲也","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kinki University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"高井, 博之","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kinki University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"唐崎, 専也","creatorNameLang":"ja"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kinki University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"石川, 欽司","creatorNameLang":"ja"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"AN00063584-19980625-0091.pdf","format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://kindai.repo.nii.ac.jp/record/2001124/files/AN00063584-19980625-0091.pdf"},"version_id":"d8dee5be-00ae-432b-88bd-81c8f322d9e7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"premature ventricular contractions","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bisoprolol","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"antiarrhythmic drugs","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Lorenz-Plot method","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"基礎疾患のない心室性期外収縮に対するβ1受容体拮抗薬(bisoprolol)の抑制効果","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"基礎疾患のない心室性期外収縮に対するβ1受容体拮抗薬(bisoprolol)の抑制効果","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"42","path":["1713338090072"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-04-23"},"publish_date":"2024-04-23","publish_status":"0","recid":"2001124","relation_version_is_last":true,"title":["基礎疾患のない心室性期外収縮に対するβ1受容体拮抗薬(bisoprolol)の抑制効果"],"weko_creator_id":"42","weko_shared_id":-1},"updated":"2024-05-10T02:12:35.331141+00:00"}