{"created":"2023-11-17T06:08:36.127376+00:00","id":2000431,"links":{},"metadata":{"_buckets":{"deposit":"831d8ec3-163f-4372-b014-39886dab934e"},"_deposit":{"created_by":42,"id":"2000431","owners":[42],"pid":{"revision_id":0,"type":"depid","value":"2000431"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:02000431","sets":["14:923:1477:1699842196626"]},"author_link":[],"control_number":"2000431","item_30002_bibliographic_information29":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023-12-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3-4","bibliographicPageEnd":"55","bibliographicPageStart":"49","bibliographicVolumeNumber":"48","bibliographic_titles":[{"bibliographic_title":"近畿大学医学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"MEDICAL JOURNAL OF KINDAI UNIVERSITY","bibliographic_titleLang":"en"}]}]},"item_30002_creator2":{"attribute_name":"作成者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"}]}],"creatorAlternatives":[{"creatorAlternative":"Kindai University","creatorAlternativeLang":"en"}],"creatorNames":[{"creatorName":"津谷, 康大","creatorNameLang":"ja"},{"creatorName":"Tsutani, Yasuhiro","creatorNameLang":"en"}]}]},"item_30002_description9":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"これまでは早期肺がんの治療は外科治療としては肺葉切除以上，周術期治療は術後補助療法としてI期を中心にtegafur-uracil，II-III期にはcisplatin併用化学療法のエビデンスが主体であった．しかし，近年の早期肺がんに対する多くの臨床試験の結果から標準治療が大きく変化してきた．外科治療では本邦の臨床試験において小型肺がんに対する区域切除を主体とした縮小手術の有用性が明らかとなり，北米の臨床試験からも縮小手術の有用性が確認された．周術期治療では本邦で新たに術後療法としてPD-L1陽性肺がんには抗PD-L1抗体であるatezolizumabやEGFR遺伝子変異陽性肺がんにはEGFR-TKIであるosimertinibが承認された．また術前療法として抗PD-1抗体nivolumabと化学療法併用療法も使用可能となり，周術期治療はかなり複雑化してきたといえる．今後も更に多くの薬剤や術前後免疫療法なども承認されることが期待されている．このような状況の中で，早期肺がんの根治を目指すために我々は治療戦略，使用薬剤，術式など多くの選択肢の中から適切な方針を選択しなくてはならない個別化治療の時代になってきたと考えられる．","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"シリーズ　最新のがん","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_30002_file35":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"AN00063584-20231215-0049.pdf","format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://kindai.repo.nii.ac.jp/record/2000431/files/AN00063584-20231215-0049.pdf"},"version_id":"c3b5504e-2bee-438b-95d8-74a50574c14b"}]},"item_30002_identifier_registration17":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.15100/0002000431","subitem_identifier_reg_type":"JaLC"}]},"item_30002_language12":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_30002_publisher10":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"近畿大学医学会","subitem_publisher_language":"ja"}]},"item_30002_resource_type13":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_30002_source_identifier22":{"attribute_name":"収録物識別子","attribute_value_mlt":[{"subitem_source_identifier":"03858367","subitem_source_identifier_type":"PISSN"},{"subitem_source_identifier":"24327190","subitem_source_identifier_type":"EISSN"}]},"item_30002_subject8":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"早期肺がん","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"区域切除","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"縮小手術","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"周術期治療","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_30002_title0":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"早期肺がん治療の転換期―縮小手術と周術期治療―","subitem_title_language":"ja"},{"subitem_title":"Major Turning Point of Treatment for Early Lung Cancer: Sublobar Resection and Perioperative Therapy","subitem_title_language":"en"}]},"item_30002_version_type15":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_title":"早期肺がん治療の転換期―縮小手術と周術期治療―","item_type_id":"40004","owner":"42","path":["1699842196626"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-12-21"},"publish_date":"2023-12-21","publish_status":"0","recid":"2000431","relation_version_is_last":true,"title":["早期肺がん治療の転換期―縮小手術と周術期治療―"],"weko_creator_id":"42","weko_shared_id":-1},"updated":"2023-12-26T05:50:57.079649+00:00"}