{"created":"2023-11-08T06:01:24.617844+00:00","id":2000369,"links":{},"metadata":{"_buckets":{"deposit":"37a43bba-792b-4fbe-abf0-be938479c326"},"_deposit":{"created_by":42,"id":"2000369","owners":[42],"pid":{"revision_id":0,"type":"depid","value":"2000369"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:02000369","sets":["14:2667:1697004343623"]},"author_link":[],"item_1693378644159":{"attribute_name":"研究分担者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"32612","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"慶應義塾大学","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"金, 倫基","creatorNameLang":"ja"},{"creatorName":"Kim, Yungi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"00620220","nameIdentifierScheme":"e-Rad"}]}]},"item_1693381679919":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"report","resourceuri":"http://purl.org/coar/resource_type/c_93fc"}]},"item_30001_bibliographic_information17":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicNumberOfPages":"7","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2022)","bibliographic_titleLang":"ja"}]}]},"item_30001_creator2":{"attribute_name":"研究代表者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"34419","affiliationNameIdentifierScheme":"kakenhi"}],"affiliationNames":[{"affiliationName":"近畿大学","affiliationNameLang":"ja"},{"affiliationName":"Kindai University","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"栗原, 新","creatorNameLang":"ja"},{"creatorName":"Kurihara, Shin","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"20630966","nameIdentifierScheme":"e-Rad"}]}]},"item_30001_description8":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"糖質に関連する難消化性成分である食物繊維は腸内細菌制御剤として盛んに利用されている一方で、タンパクに関連する難消化性成分である難消化性ペプチドは腸内細菌制御剤として未利用である。そこで、大豆由来難消化性ペプチドが腸内細菌叢へ与える影響を解析した。ヒトの腸内常在菌叢に最優勢51菌種について、難消化性ペプチドがその増殖に与える影響を純粋培養にて解析したところ、難消化性ペプチドは試験を行った11種のBacteroides属細菌のうち9菌種の増殖を抑制した。次に糞便培養系に難消化性ペプチドを添加して培養を行ったところ、Bacteroides属細菌の増殖を特異的に抑制した。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"Dietary fibre, a non-digestible component related to carbohydrates, is widely used as a modulator of gut microbiota, whereas non-digestible peptides, a protein-related non-digestible component, are not yet exploited as a modulator of gut microbiota. Therefore, we investigated the effects of non-digestible peptides from soybean on the gut microbiota. The effect of non-digestible peptides on the growth of the 51 most prevalent bacteria in the human gut commensal microbiota was analysed in culture, and found that non-digestible peptides inhibited the growth of nine of the 11 Bacteroides species tested. Next, when non-digestible peptides were added to a faecal culture system, they specifically inhibited the growth of Bacteroides spp.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"研究分野：応用微生物学","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_30001_file22":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","filename":"21K19096seika.pdf","format":"application/pdf","mimetype":"application/pdf","url":{"url":"https://kindai.repo.nii.ac.jp/record/2000369/files/21K19096seika.pdf"},"version_id":"301c82e5-3d4e-4cd6-8dd2-1fc38f69f7e5"}]},"item_30001_funding_reference15":{"attribute_name":"助成情報","attribute_value_mlt":[{"subitem_award_numbers":{"subitem_award_number":"21K19096","subitem_award_uri":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21K19096/"},"subitem_award_titles":[{"subitem_award_title":"難消化性ペプチドを用いた革新的な腸内細菌制御法の開発","subitem_award_title_language":"ja"},{"subitem_award_title":"Development of an innovative strategy to control gut microbes using indigestible peptides","subitem_award_title_language":"en"}],"subitem_funder_names":[{"subitem_funder_name":"独立行政法人日本学術振興会","subitem_funder_name_language":"ja"},{"subitem_funder_name":"Japan Society for the Promotion of Science","subitem_funder_name_language":"en"}]}]},"item_30001_language10":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_30001_subject7":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"難消化性ペプチド","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"腸内細菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Bacteroides","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"糞便培養","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト腸内常在菌叢最優勢種","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_30001_title0":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"難消化性ペプチドを用いた革新的な腸内細菌制御法の開発","subitem_title_language":"ja"},{"subitem_title":"Development of an innovative strategy to control gut microbes using indigestible peptides","subitem_title_language":"en"}]},"item_30001_version_type12":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_title":"難消化性ペプチドを用いた革新的な腸内細菌制御法の開発","item_type_id":"40001","owner":"42","path":["1697004343623"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-11-08"},"publish_date":"2023-11-08","publish_status":"0","recid":"2000369","relation_version_is_last":true,"title":["難消化性ペプチドを用いた革新的な腸内細菌制御法の開発"],"weko_creator_id":"42","weko_shared_id":-1},"updated":"2024-10-23T00:48:18.042899+00:00"}