{"created":"2023-06-20T16:47:59.325515+00:00","id":19776,"links":{},"metadata":{"_buckets":{"deposit":"1730e93e-7e89-4847-ab3d-529ae1664ad4"},"_deposit":{"created_by":3,"id":"19776","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"19776"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00019776","sets":["14:2667:4459"]},"author_link":["33632","33631","33633"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2017)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究では、肥育期間中にと畜時の枝肉成績を予測診断する指標として、血中に含まれるエクソソームに内包された分泌型miRNAからバイオマーカーの探索を実施した。miRNAマイクロアレイ解析の結果、18種類の分泌型miRNAをバイオマーカー候補としてリストアップし、さらに血中miRNAの定量分析と枝肉形質との関連の解析により、バイオマーカー候補のうち2種類のmiRNAについて再現性が確認された。国内3地域の肥育中血清を比較した結果、miRNA量に地域差が検出された。\n研究成果の概要（英文）：In this study, relations between carcass traits and exosomal miRNA expression profiles in serum were analyzed to identify circulating exosomal miRNA biomarkers for predicting carcass traits and meat quality characteristics of Japanese Black cattle by bioinformatics analysis. Eleven secreted microRNAs were listed as biomarker candidates as a result of microRNA microarray analysis using serum of fattening cattle. Subsequently, reproducibility was confirmed for the two biomarker candidate microRNAs by the association analysis between the amount of blood microRNA quantified by real-time PCR analysis and the carcass traits. Those selected microRNAs were inferred to affect the expression of genes related to differentiation and development of cells constituting muscle tissue by computational searches of existing public databases.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：挑戦的萌芽研究;  研究期間：2016～2017;   課題番号：16K15027;   研究分野：バイオインフォマティクス;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16K15027/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者/研究分担者/研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MATSUMOTO, Kazuya"},{"subitem_text_language":"en","subitem_text_value":"NAGAI,Kouhei"},{"subitem_text_language":"en","subitem_text_value":"MATSUHASHI,Tamako"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 教授"},{"subitem_text_value":"近畿大学生物理工学部; 准教授"},{"subitem_text_value":"近畿大学先端技術総合研究所; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松本, 和也"},{"creatorName":"マツモト, カズヤ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"永井, 宏平"},{"creatorName":"ナガイ, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"松橋, 珠子"},{"creatorName":"マツハシ, タマコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-11-22"}],"displaytype":"detail","filename":"16K15027seika.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"16K15027seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/19776/files/16K15027seika.pdf"},"version_id":"96161a65-9f1b-482e-8f16-ee5c152ee933"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"バイオマーカー","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"エクソソームmiRNAマーカーによる黒毛和種肥育牛の枝肉形質の生体評価は可能か？","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"エクソソームmiRNAマーカーによる黒毛和種肥育牛の枝肉形質の生体評価は可能か？"},{"subitem_title":"Is it possible to evaluate the carcass trait of fattened Japanese black cattle with exosomal microRNA markers?","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4459"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-11-22"},"publish_date":"2018-11-22","publish_status":"0","recid":"19776","relation_version_is_last":true,"title":["エクソソームmiRNAマーカーによる黒毛和種肥育牛の枝肉形質の生体評価は可能か？"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:34:23.305953+00:00"}