{"created":"2023-06-20T16:47:59.144313+00:00","id":19772,"links":{},"metadata":{"_buckets":{"deposit":"84cadcd8-a91e-416d-8487-a0940de27547"},"_deposit":{"created_by":3,"id":"19772","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"19772"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00019772","sets":["14:2667:4459"]},"author_link":["33625"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2017)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：食品製造・加工過程において生成する2つの廃棄物を有効活用して、腸のビフィズス菌を増やす食品素材の生産を試みた。（1）食肉加工過程で生成するブタ胃ムチンの0-結合型糖鎖をビフィズス菌由来の酵素、あるいは菌体を用いて分解することにより、ビフィズス菌特異的な増殖活性のある2糖ガラクト-N-ビオースの生産を検討した。（2）梅干し製造過程で生成する梅酢由来の梅ポリフェノールによるビフィズス菌増殖効果を見出し、増殖の鍵酵素であるビフィズス菌由来の2種類のGH43エキソ-α-アラビノフラノシダーゼをクローニングした。梅ポリフェノールの腸内細菌フローラ改善効果について、マウスを用いて評価した。 \n研究成果の概要（英文）：The production of prebiotics for intestinal bifidobacteria from two food wastes was studied. (1) By using bifidobacterial glycosidases or cells, bifidogenic disaccharide galacto-N-biose was released from wasted mucin, which contains abundant Q-glycans. A novel 6-sulfo-N acetylglucosaminidase, an essential enzyme for degradation of terminally sulfated glycans, was identified. A bifidobacterial strain defective in incorporation of galacto-N-biose was also screened, which is suitable for production of the disaccharide. (2) Mume-polyphenols ~epared from umesu, a waste of umeboshi production, was found to enhance bifidobacterial growth. The major phenolic compound, prunose, was assimilated by B. catenulatum and B. pseudocatenulat~ which express prunose-specific ferulate esterase. Arabinan-like polysaccharides was degraded by two novel GH43 exo-α-arabinofuranosidases from B. longum. Effects of orally administrated mume-polyphenols on intestinal microbiota was evaluated using mice.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2015～2017;   課題番号：15K07448;   研究分野：微生物学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15K07448/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"ASHIDA,Hisashi"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学生物理工学部; 教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"芦田, 久"},{"creatorName":"アシダ, ヒサシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-11-22"}],"displaytype":"detail","filename":"15K07448seika.pdf","filesize":[{"value":"2.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"15K07448seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/19772/files/15K07448seika.pdf"},"version_id":"3f3bacfe-a129-4809-a6c5-2ecacbed6214"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ビフィズス菌","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"食品由来廃棄物を有効活用した新規ビフィズス菌増殖因子の創成","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"食品由来廃棄物を有効活用した新規ビフィズス菌増殖因子の創成"},{"subitem_title":"Production of novel prebiotics for intestinal bifidobacteria from food wastes","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4459"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-11-22"},"publish_date":"2018-11-22","publish_status":"0","recid":"19772","relation_version_is_last":true,"title":["食品由来廃棄物を有効活用した新規ビフィズス菌増殖因子の創成"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:34:26.924081+00:00"}