{"created":"2023-06-20T16:47:57.494781+00:00","id":19746,"links":{},"metadata":{"_buckets":{"deposit":"0dcea0ae-3e98-4bff-8771-03ac35939a99"},"_deposit":{"created_by":3,"id":"19746","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"19746"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00019746","sets":["14:2667:4459"]},"author_link":["33557"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2017)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文):2014年度に研究計画書を完成させ、2015年7月から「ガバペンチン誘導体の不応例・不耐例に対する無作為化二重盲検プラセボ対照比較試験」を遂行した。本試験(セカンドライン試験)の研究計画書の内容を記載した論文は、BMJ Openに掲載された。2017年11月末に症例集積を終了し、2018年3月までにデータセンターでのデータ固定、解析が終了した。成果報告として、2018年度の米国臨床腫瘍学会、日本緩和医療学会総会に演題登録を行い、両学会共に採択され、日本緩和医療学会では優秀演題賞に選出された。またファーストライン試験のコンセプト作成を行い、現在日豪研究者間で国際共同研究計画書を作成中である。\n研究成果の概要(英文):A protocol paper of the second line trial was published in BMJ Open (August 2017), cooperated with the research sharing organization, completed the case collection at the end of November 2017, and fixing and analyzing data was completed at the data center by March 2018. We registered an abstract of this study to the American Society of Clinical Oncology (ASCO) in 2018 and the 23rd Congress of the Japanese Society for Palliative Medicine. The theme was adopted by both academic societies and was selected as an excellent award for the 23rd Congress of the Japanese Society for Palliative Medicine. In the double-blind randomized placebo-controlled study described here, we will evaluate the efficacy of addition of duloxetine for neuropathic cancer pain refractory to opioids and gabapentinoids. The results of the trial will clarify the second-line standard treatment for cancer-related NP. Therefore, we plan to perform a head-to head RCT of duloxetine and gabapentinoids.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目:若手研究(B); 研究期間:2014~2017; 課題番号:26860486; 研究分野:緩和医療、心身医学、心療内科; 科研費の分科・細目:","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26860486/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MATSUOKA, Hiromichi"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松岡, 弘道"},{"creatorName":"マツオカ, ヒロミチ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-11-20"}],"displaytype":"detail","filename":"26860486seika.pdf","filesize":[{"value":"217.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"26860486seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/19746/files/26860486seika.pdf"},"version_id":"213973ff-7b52-430d-8d67-326ee587bccc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"がん患者","subitem_subject_scheme":"Other"},{"subitem_subject":"神経障害性疼痛","subitem_subject_scheme":"Other"},{"subitem_subject":"デュロキセチン","subitem_subject_scheme":"Other"},{"subitem_subject":"プラセボ","subitem_subject_scheme":"Other"},{"subitem_subject":"RCT","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"がん患者の神経障害性疼痛へのプレガバリン投与後のデュロキセチンの治療応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"がん患者の神経障害性疼痛へのプレガバリン投与後のデュロキセチンの治療応用"},{"subitem_title":"Use of duloxetine after pregabalin administration to neuropathic pain in cancer patients","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4459"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-11-20"},"publish_date":"2018-11-20","publish_status":"0","recid":"19746","relation_version_is_last":true,"title":["がん患者の神経障害性疼痛へのプレガバリン投与後のデュロキセチンの治療応用"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:35:11.256629+00:00"}