{"created":"2023-06-20T16:47:14.109071+00:00","id":18874,"links":{},"metadata":{"_buckets":{"deposit":"1bfc3b6f-042a-4f07-b69b-012028f108ac"},"_deposit":{"created_by":3,"id":"18874","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18874"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018874","sets":["14:2667:4374"]},"author_link":["31960","3914","31962"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2016)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：骨粗鬆症対策は検診が女性に限定される等、男性は捨て置かれている。そこで、WHOの骨折リスク予測モデルFRAXが日本人男性に適用できるかと椎体骨折を予測できるかを検討した。男性1805人を5年間追跡し、主要骨粗鬆症性骨折と椎体骨折を把握し、FRAXによる骨折確率等で骨折を予測するモデルを作成した。FRAXによる主要骨粗鬆症性骨折予測のROC曲線下面積は0.668で、FRAXが作成されたコホートでの値を上回った。椎体骨折予測の曲線下面積は0.628だったが、腰椎骨密度、年齢、BMIでより高い性能となった。FRAXは主要骨粗鬆症性骨折予測では有効だったが、椎体骨折では腰椎骨密度に及ばなかった。\n研究成果の概要（英文）：To test the validity of a fracture risk prediction model, FRAX, in Japanese men, we analyzed the data from 1805 men who had been followed for 5 years. Major osteoporotic fractures (MOFx) and morphometric vertebral fractures (vFx) were identified in 22 and 41 men, respectively, during the follow-up. Area under ROC curve of FRAX at baseline for predicting the risk of MOFx was 0.668 and was improved to 0.720 by adding trabecular bone score (TBS) and serum pentosidine levels to the model. AUC of FRAX for predicting vFx was 0.682. A model incorporating BMD, age and BMI showed a significantly greater AUC, 0.783, than FRAX alone, and was recommended to use to assess vFx.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2014～2016;   課題番号：26460788;   研究分野：医歯薬学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460788/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者/研究分担者 /研究分担者 "}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"YURA,  Akiko"},{"subitem_text_language":"en","subitem_text_value":"IKI,  Masayuki"},{"subitem_text_language":"en","subitem_text_value":"FUJITA,  Yuki"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"由良, 晶子"},{"creatorName":"ユラ, アキコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"伊木, 雅之"},{"creatorName":"イキ, マサユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"藤田, 裕規"},{"creatorName":"フジタ, ユウキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-11-01"}],"displaytype":"detail","filename":"26460788seika.pdf","filesize":[{"value":"239.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"26460788seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18874/files/26460788seika.pdf"},"version_id":"ae27237d-62a4-49e1-ae48-ff38ede37eaa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"リスク評価","subitem_subject_scheme":"Other"},{"subitem_subject":"骨折","subitem_subject_scheme":"Other"},{"subitem_subject":"骨粗鬆症","subitem_subject_scheme":"Other"},{"subitem_subject":"予防医学","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"大規模男性コホート研究による骨粗鬆症性骨折リスク評価法FRAXの有効性評価と改良","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"大規模男性コホート研究による骨粗鬆症性骨折リスク評価法FRAXの有効性評価と改良"},{"subitem_title":"Validation and improvement of a prediction model for osteoporotic fractures, FRAX, in a large-scale cohort of Japanese elderly men.","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4374"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-11-01"},"publish_date":"2017-11-01","publish_status":"0","recid":"18874","relation_version_is_last":true,"title":["大規模男性コホート研究による骨粗鬆症性骨折リスク評価法FRAXの有効性評価と改良"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:46:22.345907+00:00"}