{"created":"2023-06-20T16:47:13.451119+00:00","id":18864,"links":{},"metadata":{"_buckets":{"deposit":"d097d57d-62bf-42bc-a2c1-1ad64831652f"},"_deposit":{"created_by":3,"id":"18864","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18864"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018864","sets":["14:2667:4374"]},"author_link":["31936","31935","31937"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2016)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文):哺乳類の視交叉上核における光入力制御に係わるゲート機構を検討した。その結果、ラット視交叉上核において光照射にて遺伝子誘導が生じる腹外側部のゲートの位相が背内側部によって規定されていることが明らかとなった。さらに、ラット網膜の神経節細胞層において昼間に光入力情報を抑制するゲート機構が存在することが示唆された。また、マウス視交叉上核においてもシェル領域により、光照射にて遺伝子誘導が生じるコア領域のゲートの位相が規定されていることが明らかとなった。さらに、マウス網膜においても昼間に光入力情報を抑制するゲート機構が存在することが明らかとなった。\n研究成果の概要(英文): We investigated the mechanisms of gating system of responses to light in the suprachiasmatic nucleus (SCN), mammalian circadian center. We got several new findings. (1) In the rat, the circadian oscillator in the dorsomedial SCN (DMSCN) determines the phase of the gate, which regulate responses to photic signal in the ventrolateral SCN(VLSCN). Then the gating system also locates in the retinal ganglion cell layer. (2) In the mouse, the circadian oscillator in the shell region within SCN also determines the phase of the gate in the SCN. In addition, the retinal gating system resides in the intrinsically photosensitive retinal ganglion cells (ipRGCs).","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目:基盤研究(C); 研究期間:2014~2016; 課題番号:26460284; 研究分野:医歯薬学; 科研費の分科・細目:","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26460284/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者/研究分担者/研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"NAGANO, Mamoru"},{"subitem_text_language":"en","subitem_text_value":"KOINUMA, Satoshi"},{"subitem_text_language":"en","subitem_text_value":"MASUMOTO, Kohei"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部; 助教"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"},{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長野, 護"},{"creatorName":"ナガノ, マモル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"31935","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80155960","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"鯉沼, 聡"},{"creatorName":"コイヌマ, サトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"31936","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10340770","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"升本, 宏平"},{"creatorName":"マスモト, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"31937","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60580529","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-11-01"}],"displaytype":"detail","filename":"26460284seika.pdf","filesize":[{"value":"161.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"26460284seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18864/files/26460284seika.pdf"},"version_id":"14044203-1e83-470e-bca6-416cb9a27e43"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"視交叉上核","subitem_subject_scheme":"Other"},{"subitem_subject":"ゲート機構","subitem_subject_scheme":"Other"},{"subitem_subject":"網膜","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"体内時計中枢である視交叉上核における光入力制御に係わるゲート機構の解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"体内時計中枢である視交叉上核における光入力制御に係わるゲート機構の解明"},{"subitem_title":"The gating system of responses to light in the suprachiasmatic nucleus, the circadian center","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4374"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-11-01"},"publish_date":"2017-11-01","publish_status":"0","recid":"18864","relation_version_is_last":true,"title":["体内時計中枢である視交叉上核における光入力制御に係わるゲート機構の解明"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:46:39.816482+00:00"}