{"created":"2023-06-20T16:47:10.677812+00:00","id":18810,"links":{},"metadata":{"_buckets":{"deposit":"caaa155a-ee42-485c-85b7-4167a4fd9707"},"_deposit":{"created_by":3,"id":"18810","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"18810"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018810","sets":["14:2667:4374"]},"author_link":["31790"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2016)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：本研究では、長鎖脂肪酸がマウス精子に発現するGPR120を介してphophatidylinositol-3 kinase (PI3K)/Akt-protein kinase (Akt) およびp38 MAPK経路を活性化させることで、直進運動するマウス精子の移動速度が暴露前に比べて有意に速くなることなどを見出した。この結果は、細胞外液中の長鎖脂肪酸がシグナル分子として精子の運動性を制御するメカニズムの存在を示唆するものである。\n研究成果の概要（英文）：In the present study, activation of GPR120 induced increase in sperm motility via PI3K/Akt and p38 MAPK pathway. This evidence suggests that extracellular LCFAs act as signal molecles that regulate sperm motility through FFAR4.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2014～2016;   課題番号：26450452;   研究分野：繁殖学・神経内分泌学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-26450452/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MORIYAMA, Ryutaro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学理工学部; 講師"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森山, 隆太郎"},{"creatorName":"モリヤマ, リュウタロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"31790","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30411573","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-11-01"}],"displaytype":"detail","filename":"26450452seika.pdf","filesize":[{"value":"173.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"26450452seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18810/files/26450452seika.pdf"},"version_id":"4694d6eb-b395-4f55-991f-97410d4f6ef1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"FFAR4","subitem_subject_scheme":"Other"},{"subitem_subject":"GPR120","subitem_subject_scheme":"Other"},{"subitem_subject":"長鎖脂肪酸","subitem_subject_scheme":"Other"},{"subitem_subject":"精子","subitem_subject_scheme":"Other"},{"subitem_subject":"運動性","subitem_subject_scheme":"Other"},{"subitem_subject":"Akt","subitem_subject_scheme":"Other"},{"subitem_subject":"p38","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"長鎖脂肪酸をシグナル分子とした精子の運動性調節メカニズム","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"長鎖脂肪酸をシグナル分子とした精子の運動性調節メカニズム"},{"subitem_title":"The regulatory mechanism of sperm motility using long-chain fatty acids as signal molecules","subitem_title_language":"en"}]},"item_type_id":"8","owner":"3","path":["4374"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-11-01"},"publish_date":"2017-11-01","publish_status":"0","recid":"18810","relation_version_is_last":true,"title":["長鎖脂肪酸をシグナル分子とした精子の運動性調節メカニズム"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T21:49:13.066080+00:00"}