@article{oai:kindai.repo.nii.ac.jp:00018450, author = {Minami, Takeshi and Miura, Sayaka}, issue = {28}, journal = {理工学総合研究所研究報告, Annual reports by Research Institute for Science and Technology}, month = {Feb}, note = {[Abstract] The number of people suffering from irritable bowel syndrome (IBS) continues to increase. It is thought that in IBS the absorption of substances from food differs from that in normal people. The aim of the present study was to clarify the difference in absorption of mercury between normal and IBS using a model rat. Cold vapor atomic absorption spectrophotometry for mercury measurement can measure the inorganic mercury level, but not the organic mercury level. An improved analytical method for the measurement of mercury was developed. Indomethacin was orally administered to rats to make an IBS model rat. When methyl mercury was p.o. administered to rats on the day after indomethacin administration, the blood mercury level did not differ from the control group until six hours later. However, when methyl mercury was administered to rats two days after, the blood mercury level was observed to be higher than that of the control group from 1 hour to 6 hours. From the present results, we concluded that IBS sufferers may absorb a lot of mercury from meals in comparison with healthy people., application/pdf}, pages = {19--25}, title = {Blood mercury level after administration of methyl mercury to an irritable bowel syndrome model rat using the improved method of cold vapor atomic absorption spectrophotometry}, year = {2016}, yomi = {ミナミ, タケシ and ミウラ, サヤカ} }