{"created":"2023-06-20T16:46:35.863411+00:00","id":18111,"links":{},"metadata":{"_buckets":{"deposit":"95a97d62-17d1-4d83-b127-89d377fdbad1"},"_deposit":{"created_by":29,"id":"18111","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"18111"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018111","sets":["14:2667:4296"]},"author_link":["30486","30485","30488","30487","30489"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"4","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2015)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：我々は，血清で診断したヘリコバクター・ピロリ感染と萎縮性胃炎が，加齢性骨劣化のバイオマーカーとなるかを検討した．対象者は，J-MICCスタディの50～60代の男性参加者である．ヘリコバクター・ピロリ感染は有意に海綿骨密度低下リスクを増加させ（オッズ比1.83，95%信頼区間1.04-3.21，P=0.03），萎縮性胃炎も有意に海綿骨密度低下リスクを増加させた（オッズ比2.22，1.17-4.22，P=0.01）．ヘリコバクター・ピロリ感染も萎縮性胃炎もない群に比較して，どちらも陽性の群では有意に海綿骨密度の低下リスクが高かった（オッズ比2.65，1.27-5.55，P=0.01）．\n研究成果の概要（英文）：We intended to ascertain whether serologically determined Helicobacter pylori infection and consequent atrophic gastritis is available as a biomarker for the age-related deterioration of bone. The subjects are male participants of the Japan Multi-institutional Collaborative Cohort Study in their 50s and 60s. Helicobacter pylori infection significantly increased the risk of low trabecular bone density (odds ratio 1.83, 95 % CI 1.04-3.21, P = 0.03). Atrophic gastritis significantly increased the risk of low trabecular bone density (2.22, 1.17-4.22, 0.01). Compared with anti-Helicobacter pylori antibody (-) and atrophic gastritis (-) subjects, anti-Helicobacter pylori antibody (+) and atrophic gastritis (+) subjects were a significant high-risk group for low trabecular bone density (2.65, 1.27-5.55, 0.01).","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2013～2015;   課題番号：25460233;   研究分野：消化器内科学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25460233/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"MIZUNO, Shigeto"},{"subitem_text_language":"en","subitem_text_value":"WATANABE, Yoshiyuki"},{"subitem_text_language":"en","subitem_text_value":"KURIYAMA, Nagato"},{"subitem_text_language":"en","subitem_text_value":"INUI, Akio"},{"subitem_text_language":"en","subitem_text_value":"ASAKAWA, Akihiro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部附属病院; 教授"},{"subitem_text_value":"京都府立医科大学医学研究科; 教授"},{"subitem_text_value":"京都府立医科大学医学研究科; 准教授"},{"subitem_text_value":"鹿児島大学医学部; 教授"},{"subitem_text_value":"鹿児島大学医学部; 准教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"水野, 成人"},{"creatorName":"ミズノ, シゲト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"渡邊, 能行"},{"creatorName":"ワタナベ, ヨシユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"栗山, 長門"},{"creatorName":"クリヤマ, ナガト","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"乾, 明夫"},{"creatorName":"イヌイ, アキオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"浅川, 明弘"},{"creatorName":"アサカワ, アキヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-14"}],"displaytype":"detail","filename":"25460233seika.pdf","filesize":[{"value":"166.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"25460233seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18111/files/25460233seika.pdf"},"version_id":"32b68ad0-53ac-4725-977f-a4ebce0b82fd"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"骨粗鬆症","subitem_subject_scheme":"Other"},{"subitem_subject":"ヘリコバクター・ピロリ","subitem_subject_scheme":"Other"},{"subitem_subject":"慢性萎縮性胃炎","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"加齢性疾患の予知を目的としたバイオマーカーの検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加齢性疾患の予知を目的としたバイオマーカーの検討"},{"subitem_title":"Study on the biomarkers predicting age-related diseases","subitem_title_language":"en"}]},"item_type_id":"8","owner":"29","path":["4296"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-14"},"publish_date":"2016-10-14","publish_status":"0","recid":"18111","relation_version_is_last":true,"title":["加齢性疾患の予知を目的としたバイオマーカーの検討"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T22:08:03.997059+00:00"}