{"created":"2023-06-20T16:46:35.668645+00:00","id":18108,"links":{},"metadata":{"_buckets":{"deposit":"3d28151b-eee5-4da7-9979-4c2f44bcf160"},"_deposit":{"created_by":29,"id":"18108","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"18108"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018108","sets":["14:2667:4296"]},"author_link":["30479","30480","30481"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2015)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：様々な心疾患の終末像である心不全に対する新たな治療制御システムとして、鍼刺激療法を導入すべく、心臓交感神経活動を確実に抑制する刺激点の探索を行った結果、耳介への鍼刺激が腎臓交感神経活動だけでなく確実に心臓交感神経活動を抑制することが明らかとなった。また、耳介鍼刺激療法との比較のため、従来の心不全治療薬として使用されてきたカルシウム拮抗薬やβ遮断薬の降圧作用および交感神経活動への影響を調べた結果、これらの薬剤では中枢性の交感神経抑制効果は認められないことがわかった。これらの結果から、耳介鍼刺激療法は、心不全への新たな治療制御システムとして有望であると考えられた。\n研究成果の概要（英文）：We investigated the stimulation point that decreased cardiac sympathetic nerve activity consistently in order to introduce acupuncture stimulation therapy as a novel system for controlling heart failure. As a result, acupuncture stimulation to the auricle always suppressed not only renal sympathetic nerve activity but also cardiac sympathetic nerve activity. As a comparison to the effect of auricular acupuncture stimulation, we investigated the effects of calcium channel blockers or beta blockers on blood pressure and sympathetic nerve activity. As a result, we showed that these agents did not decrease sympathetic nerve activity. In summary, it was suggested that the auricular acupuncture stimulation was promising as a novel system for controlling heart failure.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2013～2015;   課題番号：25350909;   研究分野：循環器内科学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25350909/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"連携研究者"},{"subitem_text_value":"連携研究者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"YAMAMOTO, Hiromi"},{"subitem_text_language":"en","subitem_text_value":"KAWADA, Toru"},{"subitem_text_language":"en","subitem_text_value":"MIYAMOTO, Tadayoshi"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"国立研究開発法人国立循環器病研究センター循環動態制御部; 室長"},{"subitem_text_value":"森ノ宮医療大学保健医療学部; 教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山本, 裕美"},{"creatorName":"ヤマモト, ヒロミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"30479","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10528582","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"川田, 徹"},{"creatorName":"カワダ, トオル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"30480","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30243752","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"宮本, 忠吉"},{"creatorName":"ミヤモ, タダヨシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"30481","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40294136","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-14"}],"displaytype":"detail","filename":"25350909seika.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"25350909seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18108/files/25350909seika.pdf"},"version_id":"efca191b-3f86-4216-8143-ff9ab7a0f838"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"耳介鍼刺激","subitem_subject_scheme":"Other"},{"subitem_subject":"心臓交感神経活動","subitem_subject_scheme":"Other"},{"subitem_subject":"降圧作用","subitem_subject_scheme":"Other"},{"subitem_subject":"心拍数","subitem_subject_scheme":"Other"},{"subitem_subject":"カルシウム受容体","subitem_subject_scheme":"Other"},{"subitem_subject":"β受容体","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"鍼刺激療法を用いた心不全に対する新規制御システムの構築","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"鍼刺激療法を用いた心不全に対する新規制御システムの構築"},{"subitem_title":"Development of a novel therapeutic system for heart failure using acupuncture stimulation","subitem_title_language":"en"}]},"item_type_id":"8","owner":"29","path":["4296"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-14"},"publish_date":"2016-10-14","publish_status":"0","recid":"18108","relation_version_is_last":true,"title":["鍼刺激療法を用いた心不全に対する新規制御システムの構築"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T22:07:58.713759+00:00"}