{"created":"2023-06-20T16:46:35.517585+00:00","id":18105,"links":{},"metadata":{"_buckets":{"deposit":"5d763f77-2db4-4a4e-9795-5568b5948926"},"_deposit":{"created_by":29,"id":"18105","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"18105"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018105","sets":["14:2667:4296"]},"author_link":["4183","4167","30473","3301","4274"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2015)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要(和文):腎細胞癌に対する新規ペプチドワクチン(5種類のターゲット分子)の開発に着手し、HLA-A24拘束性の新規ペプチド(EPOR、PDL1、HIF1)を同定した。EPOR、PDL1ワクチンの特許を申請し、HIF1については準備中である。また、以前に開発したCA9およびVEGFR1ペプチドワクチンをあわせて、マルチペプチドワクチンを確立した。\n研究成果の概要(英文):We have been working on the development of new MHC-class-I restricted peptide vaccines for five independent therapeutic targets and have identified a significant candidate EPOR, PDL1 and HIF1. We made the application of patents for EPOR and PDL1 peptide vaccine and are preparing the application for HIF1. Together with CA9 and VEGFR1 previously developed peptide vaccines, we established multi-peptide vaccination system using these five peptide vaccines.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目:基盤研究(B); 研究期間:2013~2015; 課題番号:25293336; 研究分野:泌尿器腫瘍学; 科研費の分科・細目:","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25293336/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"UEMURA, Hirotsugu"},{"subitem_text_language":"en","subitem_text_value":"DEVELASCO, Marco"},{"subitem_text_language":"en","subitem_text_value":"MINAMI, Takafumi"},{"subitem_text_language":"en","subitem_text_value":"HARADA, Mamoru"},{"subitem_text_language":"en","subitem_text_value":"YOSHIMURA, Kazuhiro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 助教"},{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"島根大学医学部; 教授"},{"subitem_text_value":"近畿大学医学部; 教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"植村, 天受"},{"creatorName":"ウエムラ, ヒロツグ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4274","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"90213397","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"デベラスコ, マルコ"},{"creatorName":"デベラスコ, マルコ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4167","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20449838","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"南, 高文"},{"creatorName":"ミナミ, タカフミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"3301","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"70340809","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"原田, 守"},{"creatorName":"ハラダ, マモル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"30473","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"50260716","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"吉村, 一宏"},{"creatorName":"ヨシムラ, カズヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"4183","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20283757","nameIdentifierScheme":"研究者番号","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-14"}],"displaytype":"detail","filename":"25293336seika.pdf","filesize":[{"value":"291.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"25293336seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18105/files/25293336seika.pdf"},"version_id":"67572fee-22da-417a-819e-068034d4d3e9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"腎細胞癌","subitem_subject_scheme":"Other"},{"subitem_subject":"癌ワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"ペプチドワクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"免疫療法","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"腎細胞癌に対するマルチペプチドワクチンの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腎細胞癌に対するマルチペプチドワクチンの開発"},{"subitem_title":"Development of multi-peptide tumor vaccine for renal cell carcinoma","subitem_title_language":"en"}]},"item_type_id":"8","owner":"29","path":["4296"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-14"},"publish_date":"2016-10-14","publish_status":"0","recid":"18105","relation_version_is_last":true,"title":["腎細胞癌に対するマルチペプチドワクチンの開発"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T22:09:10.156270+00:00"}