{"created":"2023-06-20T16:46:34.984769+00:00","id":18093,"links":{},"metadata":{"_buckets":{"deposit":"decd86ee-f23d-4d4a-8d33-fdae44675c5d"},"_deposit":{"created_by":29,"id":"18093","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"18093"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00018093","sets":["14:2667:4296"]},"author_link":["30413","30396","3701"],"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2015)"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文）：培養細胞等を用いて品質改善に役立つ成分を調べた。ヒト正常線維芽細胞を用いてUV誘導光老化を抑制する成分を検討し，植物エキスXが細胞内活性酸素濃度と活性酸素種で活性化されるp38MAPKの活性を低下させることを確認した。腸管吸収モデルとしてヒト結腸癌由来のCaco-2細胞を用い，野菜圧搾液中の水銀吸収阻害物質をスクリーニングした。その結果，分子量3000前後のシシトウ成分に高い水銀吸収阻害活性が認められた。活魚の血管への抗酸化物質の注射によって，カテキン130μmol/gとL-アスコルビン酸ナトリウム1.3μmol/gが同等のメト化抑制効果を持ち，pHと破断強度の低下も抑制することを確認した。\n研究成果の概要（英文）：UV-induced photoaging effect was examined by human normal fibroblast. Plant extract X reduced the concentration of reactive oxygen species (ROS) in cells and p38MAPK activity which was activated by ROS. The human colon cancer cell line Caco-2 was used as an intestinal absorption model. Mercury absorption inhibitors of various vegetables squeezing olution were screened. High mercury absorption inhibitory activity was observed in green pepper component of which molecular weight was around 3000. It was found that 130 μmol/g of catechin and 1.3 μmol/g of sodium L-ascorbic acid had equivalents of inhibition effect of metmyoglobin formation, also suppression effects of lowering of pH and breaking strength by injection into the blood vessels of live fish.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2013～2015;   課題番号：25450285;   研究分野：水産化学;   科研費の分科・細目：","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-25450285/"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"TSUKAMASA, Yasuyuki"},{"subitem_text_language":"en","subitem_text_value":"ANDO, Masashi"},{"subitem_text_language":"en","subitem_text_value":"ITOH, Tomohiro"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学農学部; 教授"},{"subitem_text_value":"近畿大学農学部; 教授"},{"subitem_text_value":"近畿大学農学部; 准教授"}]},"item_8_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Kindai University"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"塚正, 泰之"},{"creatorName":"ツカマサ, ヤスユキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"安藤, 正史"},{"creatorName":"アンドウ, マサシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"伊藤, 智弘"},{"creatorName":"イトウ, トモヒロ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-12"}],"displaytype":"detail","filename":"25450285seika.pdf","filesize":[{"value":"746.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"25450285seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/18093/files/25450285seika.pdf"},"version_id":"4f3cf6ad-849b-4937-99ea-da78cbf67f44"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"細胞培養","subitem_subject_scheme":"Other"},{"subitem_subject":"繊維芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"光老化","subitem_subject_scheme":"Other"},{"subitem_subject":"水銀","subitem_subject_scheme":"Other"},{"subitem_subject":"メト化","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"培養細胞を利用した養殖クロマグロ品質改善システムの構築","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"培養細胞を利用した養殖クロマグロ品質改善システムの構築"},{"subitem_title":"Study on the systems of improving meat qualities using cultured cell","subitem_title_language":"en"}]},"item_type_id":"8","owner":"29","path":["4296"],"pubdate":{"attribute_name":"公開日","attribute_value":"2016-10-12"},"publish_date":"2016-10-12","publish_status":"0","recid":"18093","relation_version_is_last":true,"title":["培養細胞を利用した養殖クロマグロ品質改善システムの構築"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2023-06-20T22:08:47.652035+00:00"}