@techreport{oai:kindai.repo.nii.ac.jp:00013997, author = {由良, 晶子 and 伊木, 雅之 and 玉置, 淳子 and 平野, 豊}, month = {Jan}, note = {研究成果の概要(和文): JPOS研究の15年追跡期間中の心血管疾患発生有無別で、骨折既往歴の有無、骨密度、骨代謝指標について有意な差は認めなかったが、10年追跡時に65歳未満であった者では、動脈硬化関連指標である足関節上腕血圧比(ABI)の年間変化率が、年齢、ABI、骨密度の値と独立して、骨密度の年間変化率と有意な正の相関を示し、骨密度の減少の度合いが大きい程、動脈硬化の進展が大きくなる可能性が示唆された。研究成果の概要(英文): Previous osteoporotic fracture, bone mineral density values, or bone turnover markers did not differ significantly between subjects with and without cardiovascular events in 15-year follow-up period of the Japanese Population-based Osteoporosis (JPOS) Cohort Study. In women aged younger than 65 year old at the 10-year follow-up survey, an annual change of ankle brachial index (ABI) during 5-year follow-up which is one of the index of atherosclerosis was significantly and positively correlated with an annual change of bone mineral density at the total hip and femoral neck during the same period independently of age, bone mineral density, and ABI values. Bone loss may be associated with advancing in atheroscl erosis in women aged younger than 65 year old., 研究種目:基盤研究(C); 研究期間:2011~2013; 課題番号:23590824; 研究分野:医歯薬学; 科研費の分科・細目:社会医学・公衆衛生学・健康科学, application/pdf}, title = {骨粗鬆症と骨折は動脈硬化を進展させ心血管リスクを高めるか--無作為標本の15年追跡}, year = {2013}, yomi = {ユラ, アキコ and イキ, マサユキ and タマキ, ジュンコ and ヒラノ, ユタカ} }