{"created":"2023-06-20T16:43:10.849173+00:00","id":13991,"links":{},"metadata":{"_buckets":{"deposit":"d21fb887-3e4c-4a7d-9c34-4294fe6f3df1"},"_deposit":{"created_by":3,"id":"13991","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13991"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00013991","sets":["14:2667:2671:2672"]},"author_link":["25664","25666","25665"],"item_8_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Morphological approach to mechanisms of light input and synchronization to the circadian oscillator"}]},"item_8_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"5","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"科学研究費助成事業研究成果報告書 (2013. )"}]}]},"item_8_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"研究成果の概要（和文): 視交叉上核における入力系および同調機構を検討した. その結果, 視交叉上核は周期の異なる２領域, 最内側領域に周期の短い領域と外側領域に長い周期を持つ細胞群がそれぞれ存在することが明らかとなった. そして, これらの領域間においてcAMPを同期シグナルとしていることが考えられた. また, 視交叉上核への光シグナルの入力制御機構の１つであるゲート機構の位相を規定しているのは視交叉上核の背内側部であることが明らかとなった.           研究成果の概要（英文): We investigated the mechanisms of light input and synchronization in the suprachiasmatic nucleus (SCN). Using rPer2 promoter::Luciferase rat, we have found that the SCN is divided into two regions in relevance to period length. One of which showed medial region of the SCN containing oscillators with a period shorter than 24 hours (SPR) and lateral region with a period longer than 24 hours (LPR). And we have found that synchrony between SPR and LPR is possibly attained by cAMP signaling. Then, We observed Per1 and cFos induction in the SCN by light when the environmental LD cycle (12:12-h) was abruptly changed to dissociate the dorsomedial SCN (DMSCN) and ventrolateral SCN (VLSCN). As a result, the phase shifting of the gate corresponded well with that of the DMSCN. The finding suggested that the DMSCN determines the phase of the gate.","subitem_description_type":"Abstract"}]},"item_8_description_36":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究種目：基盤研究(C);  研究期間：2011～2013;   課題番号：23590248;   研究分野：医歯薬学;   科研費の分科・細目：基礎医学・解剖学一般（含組織・発生）","subitem_description_type":"Other"}]},"item_8_description_37":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Research Paper","subitem_description_type":"Other"}]},"item_8_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_8_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学"}]},"item_8_relation_11":{"attribute_name":"著者 外部リンク","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/80155960.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/10340770.ja.html"}]},{"subitem_relation_name":[{"subitem_relation_name_text":"http://kaken.nii.ac.jp/d/r/60580529.ja.html"}]}]},"item_8_text_10":{"attribute_name":"著者 役割","attribute_value_mlt":[{"subitem_text_value":"研究代表者"},{"subitem_text_value":"研究分担者"},{"subitem_text_value":"研究分担者"}]},"item_8_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"NAGANO, Mamoru"},{"subitem_text_language":"en","subitem_text_value":"KOINUMA, Satoshi"},{"subitem_text_language":"en","subitem_text_value":"MASUMOTO, Kohei"}]},"item_8_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部; 准教授"},{"subitem_text_value":"近畿大学医学部; 講師"},{"subitem_text_value":"近畿大学医学部; 助教"}]},"item_8_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長野,  護"},{"creatorName":"ナガノ, マモル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"鯉沼,  聡"},{"creatorName":"コイヌマ, サトシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"升本,  宏平"},{"creatorName":"マスモト, コウヘイ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-03-31"}],"displaytype":"detail","filename":"KAKEN_23590248seika.pdf","filesize":[{"value":"206.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KAKEN_23590248seika.pdf","url":"https://kindai.repo.nii.ac.jp/record/13991/files/KAKEN_23590248seika.pdf"},"version_id":"44abb5fb-a3a9-4d4e-9302-2f017d01ebf9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"視交叉上核","subitem_subject_scheme":"Other"},{"subitem_subject":"同調機構","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"体内時計の中枢である視交叉上核における入力系及び同調機構の形態学的解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"体内時計の中枢である視交叉上核における入力系及び同調機構の形態学的解明"}]},"item_type_id":"8","owner":"3","path":["2672"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-10-16"},"publish_date":"2014-10-16","publish_status":"0","recid":"13991","relation_version_is_last":true,"title":["体内時計の中枢である視交叉上核における入力系及び同調機構の形態学的解明"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T23:05:35.487349+00:00"}