{"created":"2023-06-20T16:42:28.968522+00:00","id":13111,"links":{},"metadata":{"_buckets":{"deposit":"4b94361d-ee60-48d5-838c-a1b3d159a77a"},"_deposit":{"created_by":3,"id":"13111","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13111"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00013111","sets":["14:923:2193:2205","21:3039:3771:3774"]},"author_link":["24211","24213","24215","24216","24214","24212"],"item_2_alternative_title_3":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Biologically active substances in leaves of Fragaria×ananassa"}]},"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"55","bibliographicPageStart":"45","bibliographic_titles":[{"bibliographic_title":"近畿大学資源再生研究所報告"},{"bibliographic_title":"Annual report of the institute of resource recycling of Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[Synopsis] This paper showed that the results of isolation and identification of the biological active components in the extract obtained from strawberry leaves (Fragaria × ananassa cv. Ama-Ou) after harvesting of their fruits.  The tyrosinase inhibition was evaluated for potential human skin whitening, and super oxide dismutase (SOD) mimic activity was evaluated for potential antioxidation in the human body. Moreover, hyaluronidase inhibition, a—glucosidase inhibition and melanin biosynthesis inhibition test used by using B16 mouse melanoma cell line, were carried out evaluated in this experiment. The 50％  ethanol extract from strawberry leaves showed both of tyrosinase and hyaluronidase inhibition, and SOD mimic activity. Following active compounds were isolated by silica gel column chromatography and HPLC using tyrosinase inhibitory activity bioassay guided fractionation. These active compounds identified the tannin, agrimoniin and flavonoid glucosides, quercetin-3—O—D—glucopyranoside, quercetin-3—O—disaccharide, but this compound was not totally elucidated the chemical structure.  Though, three isolated active ingredients in the 50％ ethanol extract, did not show the cell propagation activity against NB1RGB cell line, all compounds showed both of antioxidant and melanin biosynthetic inhibitory activity in this study. Especially, agrimoniin was a strong tyrosinase and hyaluronidase inhibitor in them. These facts suggested that the strawberry leaves 50％ ethanol extract was utilized as food adductand cosmetic material from natural resources.","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学資源再生研究所"}]},"item_2_text_7":{"attribute_name":"著者(英)","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"OHARA, Yumi"},{"subitem_text_language":"en","subitem_text_value":"KAWAGOE, Yoshiharu"},{"subitem_text_language":"en","subitem_text_value":"KAMATA, Yasushi"},{"subitem_text_language":"en","subitem_text_value":"NOZAKI, Katsunori"},{"subitem_text_language":"en","subitem_text_value":"MORIMOTO, Masanori"},{"subitem_text_language":"en","subitem_text_value":"KOMAI, Koichiro"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学大学院農学研究科応用生命化学専攻"},{"subitem_text_value":"プラーナ株式会社"},{"subitem_text_value":"プラーナ株式会社"},{"subitem_text_value":"プラーナ株式会社"},{"subitem_text_value":"近畿大学大学院農学研究科応用生命化学専攻"},{"subitem_text_value":"近畿大学大学院農学研究科応用生命化学専攻"}]},"item_2_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Department of Applied Biological Chemistry, Graduate school of Agriculture, Kinki University"},{"subitem_text_value":"Plahna Co., Ltd."},{"subitem_text_value":"Plahna Co., Ltd."},{"subitem_text_value":"Plahna Co., Ltd."},{"subitem_text_value":"Department of Applied Biological Chemistry, Graduate school of Agriculture, Kinki University"},{"subitem_text_value":"Department of Applied Biological Chemistry, Graduate school of Agriculture, Kinki University"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"大原,  祐美"},{"creatorName":"オオハラ, ユミ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"河越,  義晴"},{"creatorName":"カワゴエ, ヨシハル","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"鎌田,  靖志"},{"creatorName":"カマタ, ヤスシ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"野崎,  勝則"},{"creatorName":"ノザキ, カツノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"森本,  正則"},{"creatorName":"モリモト, マサノリ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"駒井,  功一郎"},{"creatorName":"コマイ, コウイチロウ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-19"}],"displaytype":"detail","filename":"AA1247496X-20090331-0045.pdf","filesize":[{"value":"4.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AA1247496X-20090331-0045.pdf","url":"https://kindai.repo.nii.ac.jp/record/13111/files/AA1247496X-20090331-0045.pdf"},"version_id":"840a8480-b7cc-4e67-8a2c-a65ee7df747d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"イチゴ葉に含まれる生理活性物質","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"イチゴ葉に含まれる生理活性物質"}]},"item_type_id":"2","owner":"3","path":["2205","3774"],"pubdate":{"attribute_name":"公開日","attribute_value":"2011-07-12"},"publish_date":"2011-07-12","publish_status":"0","recid":"13111","relation_version_is_last":true,"title":["イチゴ葉に含まれる生理活性物質"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-06-20T23:18:51.996289+00:00"}