@article{oai:kindai.repo.nii.ac.jp:00011685, author = {遠藤, 敏廉 and 池田, 美知代 and 佐藤, 慶子 and 立山, 涼子 and 濱野, 真二郎 and 服巻, 保幸 and 小林, 茂}, journal = {近畿大学九州短期大学研究紀要, Research bulletin of Kyushu Junior College of Kinki University}, month = {Dec}, note = {It has been suggested that a high frequency of abnormal hemoglobin might reflect an advantage due to a reduced susceptibility to malaria. To evaluate this malaria hypothesis, we analyzed abnormal hemoglobin in two neighboring populations of Nepal: the Danuwar and the Tamang. It was hypothesized that the settlements of the former were biologically adapted to the malarial environment, whereas those of the latter were customarily adapted. We detected nine heterozygotes for the β^E mutation generating HbE in four families in the Danuwar setllement by analysis of isoelectric focusing (IEF) and high performance liquid chromatography (HPLC)., application/pdf}, pages = {67--74}, title = {ネパールにおける遺伝性ヘモグロビンE(HbE)の解析}, volume = {34}, year = {2004}, yomi = {エンドウ, トシヤス and イケダ, ミチヨ and サトウ, ケイコ and タテヤマ, リョウコ and ハマノ, シンジロウ and フクマキ, ヤスユキ and コバヤシ, シゲル} }