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  1. Public
  2. 研究紀要
  3. Acta Medica Kindai University
  4. 40(1)2015
  1. Private
  2. 研究紀要
  3. Acta medica Kinki University
  4. 40(1)2015

<Originals> Depressive symptoms in children and adolescents with orthostatic dysregulation vs. those with nephrotic syndrome

https://kindai.repo.nii.ac.jp/records/10604
https://kindai.repo.nii.ac.jp/records/10604
ef14cbd7-3454-4a37-903f-17edf6120eef
名前 / ファイル ライセンス アクション
AA0050842X-20150600-0007.pdf AA0050842X-20150600-0007.pdf (681.2 kB)
Item type ☆紀要論文 / Departmental Bulletin Paper(1)
公開日 2015-07-31
タイトル
タイトル <Originals> Depressive symptoms in children and adolescents with orthostatic dysregulation vs. those with nephrotic syndrome
言語 en
著者 Iba, Yoshinori

× Iba, Yoshinori

Iba, Yoshinori

ja-Kana イバ, ヨシノリ

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言語
言語 eng
キーワード
主題 orthostatic dysregulation, nephrotic syndrome, DSRS-C, depression, 8-OHdG
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
著者 所属
値 Department of Pediatrics, Kinki University School of Medicine
著者所属(翻訳)
値 近畿大学
版
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
出版者 名前
出版者 Kinki University Medical Association
書誌情報 en : ACTA MEDICA KINKI UNIVERSITY

巻 40, 号 1, p. 7-14, 発行日 2015-06-01
ISSN
収録物識別子タイプ ISSN
収録物識別子 03866092
抄録
内容記述タイプ Abstract
内容記述 [Abstract] Orthostatic dysregulation (OD), an autonomic imbalance manifesting dizziness upon standing up and vertigo as principal symptoms, is also considered to be a partly psychosomatic disorder because the condition is likely to be influenced by mental stress. Nephrotic syndrome (NS) can cause such stress in relation to recurrences, exacerbations, and vulnerability to infections. In this study we retrospectively investigated symptoms of depression in 7-to 15-year-old children with OD and NS using the Birleson Depression Self-Rating Scale for Children (DSRS-C). Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) was measured in NS patients as a urinary oxidative stress marker. In children with OD, DSRS-C scores were significantly higher than in a general population of elementary and junior high school students (P=0.00030 for elementary and junior high school students combined; P=0.0057 for junior high school students). In children with NS, DSRS-C scores were significantly lower than in the other elementary and junior high school students (P=0.019). Urinary 8-OHdG did not correlate significantly with the number of NS recurrences, duration of illness, or incidence of recurrence. No NS-related variable was found to be significantly correlated with oxidative stress. School absence often persists in OD patients even after somatic symptoms have been improved by drug therapy such as midodrine hydrochloride treatment, suggesting that symptoms of depression may prolong school absence in those with OD. Since the DSRS-C can rapidly quantify the severity of depression, early administration is recommended for children with OD.
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