| Item type |
☆紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2011-01-31 |
| タイトル |
|
|
タイトル |
[Case Reports] Epstein-Barr virus-associated T-cell lymphoma presenting as intractable gastric ulcers due to the vascular wall invasion 4 months before cervical nodal mass formation |
|
言語 |
en |
| 著者 |
Urase, Fumiaki
Nagare, Yasuaki
Maekura, Shunji
Wada, Yusuke
Murakami, Haruo
Ueda, Koji
Ochiai, Ken
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
chronic active Epstein-Barr virus infection, peripheral T-cell lymphoma, gastric ulcer, necrotic vasculitis |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者所属(翻訳) |
|
|
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Department of Hematology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Hematology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Clinical Pathology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Hematology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Hematology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Hematology Sakai Hospital, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Clinical Pathology Sakai Hospital, Kinki University Faculty of Medicine |
| 版 |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 名前 |
|
|
出版者 |
The Kinki University Medical Association |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 35,
号 2,
p. 123-128,
発行日 2010-12-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03866092 |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
[Abstract] We report here a 75-year-old male in whom fever and gastric perforation due to multiple gastric ulcers developed 4 months before the development of cervical lymph node swelling. At the time of disease onset, he did not show the characteristics patterns of anti-Epstein-Barr virus (EBV) antibody responses with raised antiviral capsid (VCA) and anti-early antigen (EA) antibodies. He was diagnosed with chronic active EBV infection (CAEBV) based on an increased EBV-DNA level in the peripheral blood. Four months later, biopsy specimen of the swollen lymph nodes revealed the infiltration of clonal lymphoma cells positive for CD3, CD8, Tcell-restricted intracellular antigen 1 (TIA-1), and EBV-encoded RNA (EBER). He died of progressive infection with cytomegalovirus and invasive aspergillus and intractable multiple hemorrhagic gastric ulcers. The cause of the multiple gastric ulcers could not be identified before death. Autopsy revealed the infiltration of CD8-positive T cells with the same surface phenotypes as those of the cervical malignant lymphoma to the perivascular areas of the ulcer base and necrotic vasculitis. This case suggested that EBV-associated T-cell lymphoma can cause gastric wall infiltration and organ injury without forming an extranodal mass even 4 months earlier than the formation of nodal lesions. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Maekura, Syunnji : Otiai, Ken |
| フォーマット |
|
|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
AA0050842X-20101200-0123.pdf (2.9 MB)
