| Item type |
☆紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2011-01-31 |
| タイトル |
|
|
タイトル |
[Reviews] Heterotypic cell-cell interaction mediated by Cell Adhesion Molecule-1, CADM1: Physiological, pathological and physical aspects |
|
言語 |
en |
| 著者 |
Ito, Akihiko
Hagiyama, Man
Inoue, Takao
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
neuro-immune mechanism, nervemast cell interaction, stress-related disease, IgCAM, femtosecond laser, impulsive force, cell adhesion strength |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者所属(翻訳) |
|
|
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Department of Pathology, Kinki University Faculty of Medicine |
| 著者所属(翻訳) |
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Division of Molecular Pathology, Institute of Medical Science, The University of Tokyo |
| 著者所属(翻訳) |
|
|
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Department of Pathology, Kinki University Faculty of Medicine |
| 版 |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 出版者 名前 |
|
|
出版者 |
The Kinki University Medical Association |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 35,
号 2,
p. 77-85,
発行日 2010-12-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03866092 |
| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
[Abstract] There are a plethora of important biological events that are regulated by cellular interactions among heterotypic cell types. The most typical example is innervation to endocrine cells and skeletal and smooth muscles. Recent biological achievements have identified many molecules that control these heterotypic cell-cell interactions. Although our understandings on these events have lately made remarkable advances at molecular levels, physical aspects of cellular adhesion have not been fully examined yet. Cell Adhesion Molecule-1, CADM1, is a member of the immunoglobulin superfamily, and has been so far characterized by several independent research groups, by virtue of its multiple functions involved in tumor suppression, synaptogenesis, and spermatogenesis. CADM1plays a key role as not only simple glue among cells, but also a conductor or promoter of heterotypic intercellular communications, for example, between nerve and mast cells, and smooth muscle and mast cells. Interestingly, it is now being revealed that the efficiency of CADM1-mediated intercellular communication is closely correlated with the kinetic strength of CADM1-mediated intercellular adhesion, by applying the latest laser technique |
| フォーマット |
|
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内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
AA0050842X-20101200-0077.pdf (3.9 MB)
