{"created":"2023-06-20T16:40:16.882263+00:00","id":10500,"links":{},"metadata":{"_buckets":{"deposit":"ba64e99f-59fd-4f4e-ac50-b0acdc4759d8"},"_deposit":{"created_by":3,"id":"10500","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"10500"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00010500","sets":["14:923:1519:1547","21:3039:3477:3480"]},"author_link":["20275"],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1/2","bibliographicPageEnd":"34","bibliographicPageStart":"23","bibliographicVolumeNumber":"33","bibliographic_titles":[{},{"bibliographic_title":"ACTA MEDICA KINKI UNIVERSITY","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Human T-cell leukemia virus type 1 (HTLV-1) is a human retrovirus that causes adult T-cell leukemia (ATL). ATL is a malignancy of mature CD4^＋ T cells with poor prognosis. HTLV-1 genome encodes a potent transcriptional regulator, namely, Tax, which plays a critical role in CD4^＋ T-cell transformation. However, Tax exerts its action only in the initial phase of ATL tumorigenesis because it is usually not detectable in ATL cells. A prominent role of the chemokine system is the regulation of leukocyte trafficking, including CD4^＋ T-cell. Here, we briefly summarize HTLV -1 infection and ATL and discuss the recent findings of the involvement of the chemokine system in HTLV-1 infection and ATL tumorigenesis.","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"The Kinki University Medical Association"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03866092","subitem_source_identifier_type":"ISSN"}]},"item_2_text_9":{"attribute_name":"著者所属(翻訳)","attribute_value_mlt":[{"subitem_text_value":"Department of Microbiology, Kinki University School of Medicine"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_be7fb7dd8ff6fe43","subitem_version_type":"NA"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hieshima, Kunio"},{"creatorName":"ヒエシマ, クニオ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"AA0050842X-20081200-0023.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AA0050842X-20081200-0023.pdf","url":"https://kindai.repo.nii.ac.jp/record/10500/files/AA0050842X-20081200-0023.pdf"},"version_id":"8858b3cb-56fc-46b3-9651-2482f23d7640"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HTLV-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ATL","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Tax","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chemokine","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"chemokine receptor","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Human T-cell leukemia virus type 1 (HTLV-1) infection and the chemokine system","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Human T-cell leukemia virus type 1 (HTLV-1) infection and the chemokine system","subitem_title_language":"en"}]},"item_type_id":"2","owner":"3","path":["1547","3480"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-07-06"},"publish_date":"2010-07-06","publish_status":"0","recid":"10500","relation_version_is_last":true,"title":["Human T-cell leukemia virus type 1 (HTLV-1) infection and the chemokine system"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-06-20T18:49:59.970750+00:00"}