| Item type |
☆紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2010-06-09 |
| タイトル |
|
|
タイトル |
Indications of laparoscopic myomectomy and efficacy of preoperative GnRHa therapy |
|
言語 |
en |
| 著者 |
Kotani, Yasushi
Shiota, Mitsuru
Umemoto, Masahiko
Tobiume, Takako
Shimaoka, Masao
Hoshiai, Hiroshi
|
| 言語 |
|
|
言語 |
eng |
| キーワード |
|
|
主題 |
laparoscopic myomectomy (LM), GnRHa therapy, postoperative recurrence |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者所属(翻訳) |
|
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 著者所属(翻訳) |
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 著者所属(翻訳) |
|
|
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Department of Obstetrics and Gynecology, Kinki University School of Medicine |
| 版 |
|
|
出版タイプ |
NA |
|
出版タイプResource |
http://purl.org/coar/version/c_be7fb7dd8ff6fe43 |
| 出版者 名前 |
|
|
出版者 |
The Kinki University Medical Association |
| 書誌情報 |
en : ACTA MEDICA KINKI UNIVERSITY
巻 34,
号 1,
p. 27-34,
発行日 2009-06-01
|
| ISSN |
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収録物識別子タイプ |
ISSN |
|
収録物識別子 |
03866092 |
| 抄録 |
|
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内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: The purpose of this study was to evaluate indications of laparoscopic myomectomy (LM) and the efficacy of preoperative GnRHa therapy. Methods: Study subjects were 161 patients who underwent LM between 1995 and 2007 at our hospital. Based on surgical performance, indications of LM were discussed in terms of the size and number of myomas. The efficacy of preoperative GnRHa therapy was evaluated by comparing the volume of myomas on MRI images and surgical performances. The recurrence rate after LM was evaluated by comparing the number of myomas confirmed on preoperative MRI and that actually enucleated. Statistical analysis was performed by ANOVA, Student's t-test, χ-square test and the Kaplan-Meier method. For all tests, p＜0.05 was considered significant. Results: The group with myomas ≧10cm showed significant increases in blood loss, operative time, and the rate of conversion to laparotomy compared with groups with smaller myomas. However, the number of myomas was not a factor that affected surgical performance. The myoma volume was reduced as a result of 43％ by preoperative GnRHa therapy without compromising surgical performance. No significant difference was observed on GnRHa therapy in the 4-year cumulative recurrence rate. The recurrence rate was significantly higher in the group in which there was a possiblity that some of myomas were missed and left.Discussion: The indications of LM were considered for myomas ＜10cm but not limited by the number of myomas. The postoperative recurrence rate will decrease if surgery is completed on ensuring no myoma has been overlooked by precisely identifying the preoperative myoma status on MRI. Preoperative GnRHa therapy was considered to be a factor not compromising the surgical performance and recurrence rate, but was effective as a pretreatment for LM to expand the indications. |
| フォーマット |
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|
内容記述タイプ |
Other |
|
内容記述 |
application/pdf |
AA0050842X-20090600-0027.pdf (848.5 kB)
