{"created":"2023-06-20T16:40:00.080948+00:00","id":10160,"links":{},"metadata":{"_buckets":{"deposit":"5bb6d480-9b02-4550-9af4-48dd2ae7e33a"},"_deposit":{"created_by":3,"id":"10160","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"10160"},"status":"published"},"_oai":{"id":"oai:kindai.repo.nii.ac.jp:00010160","sets":["14:923:1477:1503","21:3039:3456:3457"]},"author_link":["19034","19037","19036","19041","19035","19038","19039","19040","19042","19044","19043"],"item_2_biblio_info_21":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"40","bibliographicPageStart":"31","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"近畿大学医学雑誌"},{"bibliographic_title":"Medical journal of Kinki University","bibliographic_titleLang":"en"}]}]},"item_2_description_33":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"[抄録] 高齢者が多く侵襲度の高い食道癌術後の誤嚥性肺炎は最も危険な合併症のひとつである．高齢者の誤嚥はサブスタンスＰ（SP）の分泌低下による咳嗽反射低下がその要因とされている．食道癌周術期における血中SP 濃度と咳反射の推移および誤嚥/肺炎の発症との関連を明らかにする．胸部食道癌手術予定で文書により同意が得られた26例を対象とした．術前，術後２日目（POD2），術後７日目（POD7）に血中SP 濃度測定，クエン酸誘発咳嗽反射閾値検査を行い，誤嚥/肺炎の発症との関連を前向き臨床研究で検討する．血中SP の平均値は術前，POD2，POD7の順に108.2pg/ml，66.8pg/ml，62.2pg/mlと推移しPOD2に大きく低下した．クエン酸誘発咳嗽反射閾値は測定可能の23例中19例（82.6％）でPOD2に閾値の上昇（15例）または最大のレベル10（４例）を示した．65歳以上のＥ群と65歳未満のＹ群に分けて検討したところ肺炎は３例（Ｅ群：２例，Ｙ群：１例），不顕性誤嚥を２例（Ｅ群）に認め，全例POD2に咳嗽反射閾値の上昇をみた．Ｅ群の誤嚥/肺炎の４例はいずれも術前血中SP 濃度は40pg/ml以下でPOD2においても上昇をみなかった．食道癌術後の誤嚥/肺炎とのリスク因子を検討した結果，Ｅ群において術前の血中SP 濃度≦40pg/mlが最も有意なリスク因子と判明した（p＝0.008）．食道癌術後は血中SP 濃度の低下と咳嗽反射閾値の上昇により誤嚥性肺炎を容易に発症する状態にある．65歳以上で術前の血中SP 濃度≦40pg/mlは術後の誤嚥/肺炎に対するハイリスク群と考えられた．","subitem_description_type":"Abstract"}]},"item_2_description_41":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_2_publisher_14":{"attribute_name":"出版者 名前","attribute_value_mlt":[{"subitem_publisher":"近畿大学医学会"}]},"item_2_source_id_22":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03858367","subitem_source_identifier_type":"ISSN"}]},"item_2_text_8":{"attribute_name":"著者 所属","attribute_value_mlt":[{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部外科学教室"},{"subitem_text_value":"近畿大学医学部附属病院通院治療センター"},{"subitem_text_value":"近畿大学医学部外科学教室"}]},"item_2_version_type_12":{"attribute_name":"版","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中森,  康浩"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安田,  卓司"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"今本,  治彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加藤,  寛章"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"岩間,  密"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"白石,  治"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安田,  篤"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"彭,  英峰"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"新海,  政幸"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"今野,  元博"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"塩﨑,  均"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-02-18"}],"displaytype":"detail","filename":"AN00063584-20100325-0031.pdf","filesize":[{"value":"415.2 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