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        <identifier>oai:kindai.repo.nii.ac.jp:00003102</identifier>
        <datestamp>2023-06-21T01:46:36Z</datestamp>
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          <dc:title>１型糖尿病発症メカニズム解明と早期診断システムの構築</dc:title>
          <dcterms:alternative>The investigation of the cause of type 1 diabetes and the development of its prediction system.</dcterms:alternative>
          <jpcoar:creator>
            <jpcoar:creatorName>馬場谷,  成</jpcoar:creatorName>
            <jpcoar:creatorName xml:lang="ja-Kana">ババヤ, ナル</jpcoar:creatorName>
          </jpcoar:creator>
          <jpcoar:subject subjectScheme="Other">エネルギー</jpcoar:subject>
          <jpcoar:subject subjectScheme="Other">糖質代謝異常</jpcoar:subject>
          <datacite:description descriptionType="Abstract">研究成果の概要（和文）：１型糖尿病は難治性疾患であり、そのメカニズム解明と、疾患の早期発見・早期治療のためのシステム構築が急務である。本研究では、糖尿病症状出現前の１型糖尿病をとらえる最も有用な手段であるインスリン抗体の高感度検出法を確立し、その成果を報告した。また、１型糖尿病メカニズム解明に重要な糖尿病疾患感受性遺伝子を明らかにするとともに、早期診断のためのスクリーニングパネルを作製した。         研究成果の概要（英文）：The intervention of type 1 diabetes is difficult and not enough successfully at the moment, and therefore the only way for the eradication of type 1 diabetes is prediction, and consequent prevention of the disease. The aim of this study is to discover genetic determinants of type 1 diabetes, and to develop a prediction system for type 1 diabetes. In this study, I succeeded in the construction of new assay for insulin autoantibody. In addition, I developed a screening panel for early diagnosis of type 1 diabetes.</datacite:description>
          <datacite:description descriptionType="Other">研究種目：若手研究（B）;   研究期間：2009～2010;   課題番号：21790885;    研究分野：医歯薬学;    科研費の分科・細目：内科系臨床医学・代謝学</datacite:description>
          <datacite:description descriptionType="Other">Research Paper</datacite:description>
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          <dc:publisher>近畿大学</dc:publisher>
          <datacite:date dateType="Issued">2010-01-01</datacite:date>
          <dc:language>jpn</dc:language>
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            <jpcoar:relatedTitle>https://kaken.nii.ac.jp/ja/r/10449837</jpcoar:relatedTitle>
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          <jpcoar:sourceTitle>科学研究費補助金研究成果報告書 (2010. )</jpcoar:sourceTitle>
          <jpcoar:pageStart>1</jpcoar:pageStart>
          <jpcoar:pageEnd>6</jpcoar:pageEnd>
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            <datacite:date dateType="Available">2016-02-17</datacite:date>
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