2026-03-09T03:26:09Z https://kindai.repo.nii.ac.jp/oai

oai:kindai.repo.nii.ac.jp:00002117 2023-06-21T02:16:00Z 14:2529:2619:2633 21:2532:2621:2634

Loss of energy consumption during muscular contraction in partially denervated regenerating frog sartorius muscle 脱神経されたカエル再生骨格筋の筋収縮とエネルギ-代謝の減少について Takashima, Masahiro タカシマ, マサヒロ muscle regeneration ^<31>P-NMR spectroscopy energy metabolism muscular contractile activity [Abstract] 1.The dynamics of the response of partially denervated regenerating frog sartorius muscle to muscular contraction were investigated by in vivo ^<31>P-NMR spectroscopy. 2.Morphologically, muscle stump became occupied with muscle fibers and showed no significant differences from controls eight weeks after the operation. The frog skeletal muscle seemed to regenerate not only muscle stumps but denervated and innervated sites ofthe muscle. 3.Compared with innervated and control muscles, denervated regenerating muscle showed low tetanic tension and small changes in the relative concentrations of PCr to β-ATP, Pi to β-ATP, and in intracellular pH value with direct muscle stimulation. 4.These results suggested that partially denervated regenerating muscle may have reduced consumption of high-energy phosphate compounds resulting in a decrease in muscularcontraction, or have decreased muscular contractile activity resulting in a reduction in the consumption of high-energy compounds. 学位の種類：医学　　学位授与年月日：1995/3/25　指導： 秩父, 志行 教授(Director: Prof. Chichibu, Shiko)　　報告番号：甲第299号　　学内授与番号：医甲241　　NDL書誌ID：000000286567 application/pdf 近畿大学 1995-01-01 eng thesis VoR https://kindai.repo.nii.ac.jp/records/2117 博士学位論文 Thesis or Dissertation 1 14 https://kindai.repo.nii.ac.jp/record/2117/files/Thesis_Mek0241-19950325-0001.pdf application/pdf 775.0 kB 2016-02-17